• 姓名: 吴加胜
  • 性别: 男
  • 职称: 副研究员
  • 职务: 
  • 学历: 博士研究生
  • 电话: 010-82543475
  • 传真: 
  • 电子邮件: wujs@mail.ipc.ac.cn
  • 通讯地址: 北京市海淀区中关村东路29号
    简  历:
  •   吴加胜,男,生于19783月,现任中国科学院理化技术研究所副研究员。20067毕业于中国科学院理化技术研究所,获理学博士学位。20069-20078月,于韩国Dankook University化学系从事博士后工作一年;20079-20097月,在香港城市大学生物化学系从事博士后工作近两年。20097月回理化所光响应材料与器件研究组工作,同年被遴选为硕士生导师。主要从事荧光化学传感分子的设计合成及其在环境、生物、医学方面的应用等研究工作。目前已发表文章40余篇,其中有三篇文章目前引用超过150次,两篇文章曾入选美国化学会期刊Organic Letters近三年来引用次数最多的20篇论文之一,部分研究成果受到同行们的广泛关注。最近所在课题组应邀在Chemical Society Reviews上发表题为“New Sensing Mechanisms for Design of Fluorescent Chemosensors Emerging in Recent Years”综述文章,对近年来出现的新型的荧光传感机制进行了系统的阐述。 

    社会任职:
    研究方向:
  • 1.荧光化学传感分子的设计、合成及在生物传感领域的应用; 

    2.用于检测生物水解酶的荧光探针分子的设计与合成; 

    3. 光化学氧化反应

    承担科研项目情况:
  •   1. 用于高灵敏检测磷酸水解酶的新型荧光探针的设计(自然科学基金面上项目,课题负责人) 

      2. 用于检测谷胱甘肽还原酶的荧光传感分子的设计(自然科学基金主任基金,课题负责人)  

      3. 基于质子转移和能量转移的荧光探针的设计及其用于磷酸水解酶的高灵敏检测(中科院理化所青年基金,课题负责人) 

    代表论著:
  •   1. Jiasheng Wu, Ruilong Sheng, Weimin Liu, Pengfei Wang, Jingjin Ma, and Hongyan Zhang, “Fluorescent Sensors Based on Controllable Conformational Change for Discrimination of Zn2+ over Cd2+”, Tetrahedron., 2012, 68, 5458–5463. 

      2. Jiasheng Wu, Ruilong Sheng, Weimin Liu, Pengfei Wang, Hongyan Zhang, and Xiaoqing Zhuang, “Reversibly Fluorescent Probe for Highly Selective and Sensitive Detection of Mercapto Biomolecules”, Inorg. Chem., 2011, 50, 6543–6551. 

      3. Jiasheng Wu, Weimin Liu, Jiechao Ge, Hongyan Zhang, and Pengfei Wang, “New Sensing Mechanisms for Design of Fluorescent Chemosensors Emerging in Recent Years”, Chem. Soc. Rev., 2011, 40, 3483–3495. (Times cited: 125)  

        4. Minhuan Lan, Jiasheng Wu, Jiechao Ge, Weimin Liu, Hongyan Zhang, Jiayu Sun, Wenwen Zhao, Wenjun Zhang, and Pengfei Wang, “Copolythiophene-Derived Colorimetric and Fluorometric Sensor for Highly Sensitive Determination of Lipopolysaccharide”, J. Am. Chem. Soc., 2012, 134 , 6685–6694. 

      5. Kyoung Chul Ko, Jiasheng Wu, Hyun Jung Kim, Pil Seung Kwon, Jong Wan Kim, Richard A. Bartsch, Jin Yong Lee, and Jong Seung Kim, “Rationally Designed Fluorescence ‘Turn-On’ Sensor for Cu2+”, Chem. Commun., 2011, 47, 3165–3167. 

      6. Minhuan Lan, Jiasheng Wu, WeiminLiu, Hongyan Zhang, Wenjun Zhang, Xiaoqing Zhuang, Pengfei Wang, “Highly Sensitive Fluorescent Probe for Thoils Based on Combination of PET and ESIPT Mechanisms”, Sensor Actuat B-Chem. 2011, 156, 332–337. 

      7. Lintao Zeng, Jiasheng Wu, Qing Dai, Weimin Liu, Pengfei Wang, and Chun-Sing Lee, “Sensing of Bacterial Endotoxin in Aqueous Solution by Supramolecular Assembly of Pyrene Derivative”, Org. Lett., 2010, 12, 4014–4017. 

      8. Jiasheng Wu, In-Chul Hwang, Kwang S. Kim and Jong Seung Kim, “Rhodamine-Based Hg2+-Selective Chemodosimeter in Aqueous Solution: Fluorescent OFF-ON”, Org. Lett., 2007, 9, 907–910. (Times cited: 239) (#曾入选美国化学会期刊Organic Letters近三年来引用次数最多的20篇论文之一) 

      9. Jiasheng Wu, Weimin Liu, Xiaoqing Zhuang, Fang Wang, Pengfei Wang, Silu Tao, Xiaohong Zhang, Shikang Wu and Shuittong Lee, “Fluorescence Turn-on of Coumarin Derivatives by Metal Cations: A New Signaling Mechanism Based on C=N Isomerization”, Org. Lett., 2007, 9, 33–36. (Times cited: 157) 

      10. Min Hee Lee, Jiasheng Wu, Jeong Won Lee, Jong Hwa Jung and Jong Seung Kim, “Highly Sensitive and Selective Chemosensor for Hg2+ Based on the Rhodamine Fluorophore”, Org. Lett., 2007, 9, 2501–2504. (Times cited: 187) (#曾入选美国化学会期刊Organic Letters近三年来引用次数最多的20篇论文之一) 

    获奖及荣誉: